Article
Chlamydia pneumoniae infection, complement factor H variants and age-related macular degeneration.
The British journal of ophthalmology - 1 Mar 2009
Shen D, Tuo J, Patel M, Herzlich A A, Ding X, Chew E Y, Chan C-C
Abstract excerpt
BACKGROUND/AIMS: Impaired inhibition of the alternative complement pathway by complement factor H (CFH) is linked to age-related macular degeneration (AMD) based on the strong association between CFH variant and AMD. Chlamydia pneumoniae (C pneumoniae) infection can trigger the alternative pathwa...
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