Article
Neuroactive Steroid Levels in a transgenic rat model of CMT1A Neuropathy.
Journal of molecular neuroscience : MN - 1 Mar 2008
Caruso Donatella, Scurati Samuele, Roglio Ilaria, Nobbio Lucilla, Schenone Angelo, Melcangi Roberto C
Abstract excerpt
Charcot-Marie-Tooth type 1A (CMT1A) represents 80% of all the demyelinating hereditary motor and sensory neuropathies. As recently suggested, neuroactive steroids may have a role in a therapeutic strategy for peripheral neuropathies, including CMT1A. To this aim, an accurate qualitative and quantitative analysis of neuroactive steroid levels in this disease could be extremely important to define effective...
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