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[Establishment and use of infectious bacterial artificial chromosome (BAC) DNA clones of animal herpesviruses].

Berliner und Munchener tierarztliche Wochenschrift - 1 Jan 2000

Osterrieder Nikolaus, Schumacher Daniel, Trapp Sascha, Beer Martin, von Einem Jens, Tischer Karsten

Abstract excerpt

Since the first description of the cloning und mutagenesis of a herpesviral genome in 1997, a number of herpesviral DNA's have been cloned as bacterial artificial chromosomes (BACs). Herpesvirus BAC's are established by introduction of a mini F origin of replication into the viral genome, which can as such be maintained und manipulated in Escherichia coli as a single copy extrachromosomal DNA. Herpesvirus DNA's...

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PMID: 14526467

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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