[Gene structure of the human MHC region].

Abstract excerpt

The human major histocompatibility complex (MHC) encodes the highly polymorphic human leukocyte antigens (HLA) responsible for antigen presentation to T cells. The HLA gene complex is located on the short arm of chromosome 6 within 6p21.3 and covers a distance of about 4,000 kb that has arisen through repeated gene duplication and conversion during evolution. The HLA class I region is about 2,000 kb in size,...

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