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Mitochondrial DNA transmission and transcription after somatic cell fusion to one or more cytoplasts.

Stem cells (Dayton, Ohio) - 1 Mar 2008

Bowles Emma J, Tecirlioglu R Tayfur, French Andrew J, Holland Michael K, St John Justin C

Abstract excerpt

Following fertilization, mitochondrial DNA is inherited from the oocyte and transmitted homoplasmically. However, following nuclear transfer, mitochondrial DNA can be transmitted from both the donor cell and recipient oocyte, resulting in a state of heteroplasmy. To determine whether the genetic diversity between donor cell and recipient cytoplast mitochondrial DNA influences development, we generated bovine...

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PMID: 18192233
DOI: 10.1634/stemcells.2007-0747

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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