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Article

Epigenetic and experimental modifications in early mammalian development: Part I: Mitochondria: potential roles in embryogenesis and nucleocytoplasmic transfer

1 Mar 2001

Abstract excerpt

This review examines current understanding of mammalian mitochondria and mitochondrial DNA in the light of new reproductive technologies. Mitochondria are central to ageing, apoptosis, metabolism and many diseases. They are controlled by a dual genome system, with cooperation between endogenous mitochondrial genes and mitochondrial genes translocated to the nucleus over the course of evolution. This translocation...

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PMID: 11284664
DOI: 10.1093/humupd/7.2.217

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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