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Article

Fate of donor mitochondrial DNA in cloned bovine embryos produced by microinjection of cumulus cells.

Biology of reproduction - 1 Aug 2002

Do Jeong Tae, Lee Jeong Woong, Lee Bo Yon, Kim Seung Bo, Ryoo Zae Young, Lee Hoon Taek, Chung Kil Saeng

Abstract excerpt

This study examined the fate of donor mitochondrial DNA during preimplantation development after nuclear transfer (NT) in cattle. Frozen-thawed cumulus cells were used as donor cells in the nuclear transfer. Mitochondrial DNA heteroplasmy in the nuclear transfer embryos was analyzed by allele-specific PCR (AS-PCR), direct DNA sequencing, and DNA chromatography. AS-PCR analysis for the detection of donor...

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PMID: 12135895
DOI: 10.1095/biolreprod67.2.555

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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