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Article

In vivo validation of signaling pathways regulating human monocyte chemotaxis.

Journal of immunological methods - 31 Jan 2008

Bhattacharjee Ashish, Mishra Ravi S, Feldman Gerald M, Cathcart Martha K

Abstract excerpt

Identification of novel signal transduction pathways regulating monocyte chemotaxis can indicate unique targets for preventive therapies for treatment of chronic inflammatory diseases. To aid in this endeavor we report conditions for optimal transfection of primary human monocytes coupled with a new model system for assessing their chemotactic activity in vivo. This method can be used as a tool to identify the...

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Identifiers

PMID: 18191414
DOI: 10.1016/j.jim.2007.11.011
PMCID: PMC2292102

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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