Article
Monocytes recruited to sites of inflammation express a distinctive proinflammatory (P) phenotype.
The American journal of physiology - 1 Dec 1994
Owen C A, Campbell M A, Boukedes S S, Campbell E J
Abstract excerpt
Only a minor proportion of monocytes responds to chemoattractants. To test the possibility that chemoattractant-responsive monocytes have distinctive functional characteristics, we enriched or depleted monocyte preparations for cells having a proinflammatory (P) phenotype and tested their responses to biologically relevant chemoattractants. We prepared monocyte subpopulations by one of three independent...
Topics
- Actins
- Cell Adhesion
- Cell Movement
- Chemokine CCL2
- Chemotactic Factors
- Chemotaxis, Leukocyte
- Flow Cytometry
- HLA-DR Antigens
- Humans
- Inflammation
- Monocytes
- N-Formylmethionine Leucyl-Phenylalanine
