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Monocyte Migration Emerges from a Divergent Chemokine Signaling Network

2026-05-04

Abstract excerpt

Migration of leukocytes in the context of immune homeostasis or inflammatory diseases is regulated by activation of chemokine receptors by chemokine ligands. To elucidate how these interactions give rise to cell migration, we mapped the chemokine-stimulated signal transduction network in monocytic THP-1 cells. Global phosphoproteomics revealed 630 time-resolved changes in phosphorylated proteins downstream of the...

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Literature Corpus work
90c7e46a-b877-519a-9efa-321cbfcf1546
DOI
10.64898/2026.04.29.721539
Open publication

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Monocyte Migration Emerges from a Divergent Chemokine Signaling NetworkDOI 10.64898/2026.04.29.721539
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