Docking of axonal mitochondria by syntaphilin controls their mobility and affects short-term facilitation.

Abstract excerpt

Proper distribution of mitochondria within axons and at synapses is critical for neuronal function. While one-third of axonal mitochondria are mobile, a large proportion remains in a stationary phase. However, the mechanisms controlling mitochondrial docking within axons remain elusive. Here, we report a role for axon-targeted syntaphilin (SNPH) in mitochondrial docking through its interaction with microtubules....

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Axonal Transport
• Share to Axons
• Share to Calcium Signaling