Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dynein light chain LC8 regulates syntaphilin-mediated mitochondrial docking in axons.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 29 Jul 2009

Chen Yan-Min, Gerwin Claudia, Sheng Zu-Hang

Abstract excerpt

Mitochondria in the cell bodies of neurons are transported down neuronal processes in response to changes in local energy and metabolic states. Because of their extreme polarity, neurons require specialized mechanisms to regulate mitochondrial transport and retention in axons. Our previous studie...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Axons
Share to Cytoplasmic Dyneins
Share to Cytoskeleton

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dyneins

Share to Hippocampus

Share to Microtubule-Associated Proteins

Share to Myosin Light Chains

Share to Protein Stability

Source

Open in PubMed Open full text

Identifiers

PMID: 19641106
DOI: 10.1523/JNEUROSCI.1472-09.2009
PMCID: PMC6666546

Genes

SNPH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19641106-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dynein light chain LC8 regulates syntaphilin-mediated mitochondrial docking in axons.PMID 19641106Read ↗

Docking of axonal mitochondria by syntaphilin controls their mobility and affects short-term facilitation.Semantic proximity Read ↗

Syntabulin-mediated anterograde transport of mitochondria along neuronal processes.Semantic proximity Read ↗

Releasing Syntaphilin Removes Stressed Mitochondria from Axons Independent of Mitophagy under Pathophysiological Conditions.Semantic proximity Read ↗

Proteomic Analysis of Dynein-Interacting Proteins in Amyotrophic Lateral Sclerosis Synaptosomes Reveals Alterations in the RNA-Binding Protein Staufen1.Semantic proximity Read ↗

Stathmins and Motor Neuron Diseases: Pathophysiology and Therapeutic TargetsSemantic proximity Read ↗

A pathogenic mutation in α-SNAP impairs membrane lipid binding by concealing a critical hydrophobic loop.Semantic proximity Read ↗

Neurodegenerative mutation in cytoplasmic dynein alters its organization and dynein-dynactin and dynein-kinesin interactions.Semantic proximity Read ↗

The Long Haul: Microtubule Motors as the Essential Supply Line for Neuronal Longevity.Semantic proximity Read ↗

Dynein mutations associated with hereditary motor neuropathies impair mitochondrial morphology and function with age.Semantic proximity Read ↗

Mutant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro.Semantic proximity Read ↗

Local inhibition of microtubule dynamics by dynein is required for neuronal cargo distribution.Semantic proximity Read ↗

Regulation of mitochondria-dynactin interaction and mitochondrial retrograde transport in axons.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.