Article
Mitochondrial matrix Ca2+ as an intrinsic signal regulating mitochondrial motility in axons.
Proceedings of the National Academy of Sciences of the United States of America - 13 Sept 2011
Chang Karen T, Niescier Robert F, Min Kyung-Tai
Abstract excerpt
The proper distribution of mitochondria is particularly vital for neurons because of their polarized structure and high energy demand. Mitochondria in axons constantly move in response to physiological needs, but signals that regulate mitochondrial movement are not well understood. Aside from producing ATP, Ca(2+) buffering is another main function of mitochondria. Activities of many enzymes in mitochondria are...
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