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Article

P53 represses human papillomavirus type 16 DNA replication via the viral E2 protein.

Virology journal - 11 Jan 2008

Brown Craig, Kowalczyk Anna M, Taylor Ewan R, Morgan Iain M, Gaston Kevin

Abstract excerpt

BACKGROUND: Human papillomavirus (HPV) DNA replication can be inhibited by the cellular tumour suppressor protein p53. However, the mechanism through which p53 inhibits viral replication and the role that this might play in the HPV life cycle are not known. The papillomavirus E2 protein is requir...

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Share to Cell Line, Tumor
Share to DNA-Binding Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Human papillomavirus 16

Share to Models, Molecular

Share to Oncogene Proteins, Viral

Share to Tumor Suppressor Protein p53

Share to Virus Replication

Source

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Identifiers

PMID: 18190682
DOI: 10.1186/1743-422X-5-5
PMCID: PMC2249571

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18190682-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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