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Article

Src and Wnt signaling regulate dynactin accumulation to the P2-EMS cell border in C. elegans embryos.

Journal of cell science - 15 Jan 2008

Zhang Haining, Skop Ahna R, White John G

Abstract excerpt

In many organisms, the dynein-dynactin complex is required for the alignment of the mitotic spindle onto the axis of polarity of a cell undergoing asymmetric cell division. How this complex transduces polarity cues, either intrinsic or extrinsic, and rotationally aligns the spindle accordingly is not well understood. The Caenorhabditis elegans blastomere P2 polarizes the neighboring EMS blastomere, which causes...

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Identifiers

PMID: 18187449
DOI: 10.1242/jcs.015966

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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