Article
Kinesin-1 interacts with Bucky ball to form germ cells and is required to pattern the zebrafish body axis.
Development (Cambridge, England) - 1 Sept 2015
Campbell Philip D, Heim Amanda E, Smith Mordechai Z, Marlow Florence L
Abstract excerpt
In animals, specification of the primordial germ cells (PGCs), the stem cells of the germ line, is required to transmit genetic information from one generation to the next. Bucky ball (Buc) is essential for germ plasm (GP) assembly in oocytes, and its overexpression results in excess PGCs in zebrafish embryos. However, the mechanistic basis for the excess PGCs in response to Buc overexpression, and whether...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
