Article
One-year longitudinal evaluation of sensorimotor functions in APP751SL transgenic mice.
Genes, brain, and behavior - 1 Feb 2008
Le Cudennec C, Faure A, Ly M, Delatour B
Abstract excerpt
Intracerebral amyloid-beta (Abeta) peptide deposition is considered to play a key role in Alzheimer's disease and is designated as a principal therapeutic target. The relationship between brain Abeta levels and clinical deficits remains, however, unclear, both in human patients and in animal mode...
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