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Article

One-year longitudinal evaluation of sensorimotor functions in APP751SL transgenic mice.

Genes, brain, and behavior - 1 Feb 2008

Le Cudennec C, Faure A, Ly M, Delatour B

Abstract excerpt

Intracerebral amyloid-beta (Abeta) peptide deposition is considered to play a key role in Alzheimer's disease and is designated as a principal therapeutic target. The relationship between brain Abeta levels and clinical deficits remains, however, unclear, both in human patients and in animal models of the disease. The purpose of the present study was to investigate, in a transgenic mouse model of brain...

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Source

Identifiers

PMID: 18184372
DOI: 10.1111/j.1601-183X.2007.00374.x

Genes

APP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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