Article
Transgenic mice expressing the betaAPP695SWE mutation: effects on exploratory activity, anxiety, and motor coordination.
Brain research - 4 Jul 2003
Lalonde R, Lewis T L, Strazielle C, Kim H, Fukuchi K
Abstract excerpt
The functional consequences of the betaAPP transgene with the Swedish mutation in mice were assessed in tests of exploratory activity and motor coordination. The betaAPP(695)SWE (Tg2576) transgenic mice are characterized by Abeta plaque formation in the neocortex and hippocampus. By comparison to...
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