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Article

Increase of virulence and its phenotypic traits in drug-resistant strains of Candida albicans.

Antimicrobial agents and chemotherapy - 1 Mar 2008

Angiolella Letizia, Stringaro Anna Rita, De Bernardis Flavia, Posteraro Brunella, Bonito Mariantonietta, Toccacieli Laura, Torosantucci Antonella, Colone Marisa, Sanguinetti Maurizio, Cassone Antonio, Palamara Anna Teresa

Abstract excerpt

There is concern about the rise of antifungal drug resistance, but little is known about comparative biological properties and pathogenicity of drug-resistant strains. We generated fluconazole (FLC; CO23 RFLC)- or micafungin (FK; CO23 RFK)-resistant strains of Candida albicans by treating a FLC- and FK-susceptible strain of this fungus (CO23 S) with stepwise-increasing concentrations of either drug. Molecular...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18180350
DOI: 10.1128/AAC.01223-07
PMCID: PMC2258496

Genes

RFK

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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