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Article

Mrr2 mutations and upregulation are associated with increased fluconazole resistance in Candida albicans isolates from patients with vulvovaginal candidiasis.

Letters in applied microbiology - 1 Feb 2020

Feng W, Yang J, Ji Y, Xi Z, Yang L, Zhu X, Ma Y

Abstract excerpt

Candida albicans is an opportunistic fungus, which causes vulvovaginal candidiasis (VVC). The aim of this study was to evaluate Mrr2 mutation and its expression levels and Candida drug resistance 1 (Cdr1) in C. albicans associated with fluconazole (FCA) resistance. We identified 80 isolates of C. albicans from 155 vaginal secretions and performed FCA drug sensitivity tests, using M27-A3 micro-broth dilution. We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 31705810
DOI: 10.1111/lam.13248

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