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Article

Changes of virulence factors accompanying the phenomenon of induced fluconazole resistance in <i>Candida albicans</i>

5 Sept 2000

Abstract excerpt

We investigated a fluconazole-sensitive (MICflu = 5 micrograms ml-1) clinical isolate and a fluconazole-resistant (MICflu > 80 micrograms ml-1) laboratory mutant Candida albicans strain developed from the sensitive one. We studied putative virulence factors including germination, adherence ability to either buccal epithelial cells or acrylate surface, the secreted aspartic proteinase, and the extracellular...

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Identifiers

PMID: 11036397
DOI: 10.1046/j.1439-0507.2000.00587.x

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