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Article

Common genetic variation in the type A endothelin-1 receptor is associated with ambulatory blood pressure: a family study.

Journal of human hypertension - 1 Apr 2008

Rahman T, Baker M, Hall D H, Avery P J, Keavney B

Abstract excerpt

The endothelins are among the most potent vasoconstrictors known. Pharmacological inhibition of endothelin receptors lowers blood pressure (BP). It is unknown whether naturally occurring genetic variation in the endothelin receptors influences BP. We have evaluated the type A endothelin receptor (EDNRA) as a candidate gene for hypertension in a large family study. A total of 1425 members of 248 families selected...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18172451
DOI: 10.1038/sj.jhh.1002322

Genes

EDNRA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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