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Article

Genes encoding endothelin-converting enzyme-1 and endothelin-1 interact to influence blood pressure in women: the EVA study.

Journal of hypertension - 1 Apr 2004

Funalot Benoît, Courbon Dominique, Brousseau Thierry, Poirier Odette, Berr Claudine, Cambien François, Amouyel Philippe, Schwartz Jean-Charles, Ducimetière Pierre

Abstract excerpt

BACKGROUND: Endothelin-1 (ET-1) is a potent vasoactive peptide that has been implicated in the regulation of basal vascular tone. Endothelin-converting enzyme-1 (ECE-1), the main enzyme responsible for ET-1 generation, may contribute to blood pressure (BP) control. A possible association between a polymorphism of the gene encoding ECE-1 (ECE1B C-338A) and BP values in untreated hypertensive women was recently...

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Source

Identifiers

PMID: 15126915
DOI: 10.1097/00004872-200404000-00016

Genes

EDN1
ECE1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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