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Article

Variation in genes in the endothelin pathway and endothelium-dependent and endothelium-independent vasodilation in an elderly population.

Acta physiologica (Oxford, England) - 1 May 2013

Lind L, Syvänen A-C, Axelsson T, Lundmark P, Hägg S, Larsson A

Abstract excerpt

AIM: Indirect evidences by blockade of the endothelin receptors have suggested a role of endothelin in endothelium-dependent vasodilation. This study aimed to investigate whether circulating levels of endotehlin-1 or genetic variations in genes in the endothelin pathway were related to endothelium-dependent vasodilation. METHODS: In 1016 seventy-year-old participants of the population-based Prospective Study of...

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Source

Identifiers

PMID: 23336501
DOI: 10.1111/apha.12068

Genes

ECE1
EDNRA
EDNRB
CRP
EDN1

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