Article
Orthostatic hypotension and novel blood pressure-associated gene variants: Genetics of Postural Hemodynamics (GPH) Consortium.
European heart journal - 1 Sept 2012
Fedorowski Artur, Franceschini Nora, Brody Jennifer, Liu Chunyu, Verwoert Germaine C, Boerwinkle Eric, Couper David, Rice Kenneth M, Rotter Jerome I, Mattace-Raso Francesco, Uitterlinden Andre, Hofman Albert, Almgren Peter, Sjögren Marketa, Hedblad Bo, Larson Martin G, Newton-Cheh Christopher, Wang Thomas J, Rose Kathryn M, Psaty Bruce M, Levy Daniel, Witteman Jacqueline, Melander Olle
Abstract excerpt
AIMS: Orthostatic hypotension (OH), an independent predictor of mortality and cardiovascular events, strongly correlates with hypertension. Recent genome-wide studies have identified new loci influencing blood pressure (BP) in populations, but their impact on OH remains unknown. METHODS AND RESULTS: A total of 38 970 men and women of European ancestry from five population-based cohorts were included, of whom 2656...
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