Article
Limited effects of beta-endorphin compared to loperamide or fentanyl in a neuroendocrine biomarker assay in non-human primates.
Psychoneuroendocrinology - 1 Apr 2008
Butelman Eduardo R, Reed Brian, Chait Brian T, Mandau Marek, Yuferov Vadim, Kreek Mary Jeanne
Abstract excerpt
The in vivo pharmacodynamics of the opioid neuropeptide beta-endorphin (a major endogenous agonist at the mu-opioid receptor) is difficult to determine in non-human primate models with translational value, or in humans. The present studies therefore employed a neuroendocrine biomarker assay, prol...
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