Article
Low efficacy opioids: implications for sex differences in opioid antinociception.
Experimental and clinical psychopharmacology - 1 Feb 2006
Barrett Andrew C
Abstract excerpt
It is becoming increasingly evident that the sex of an organism is a critical determinant of responsiveness to opioid analgesics. However, the factors that determine the magnitude and direction of sex differences in opioid antinociception have not been fully elucidated. One factor that has received attention is the relative efficacy of the opioid. This review summarizes recent findings in which opioid efficacy...
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