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Article

Molecular basis of synaptic vesicle cargo recognition by the endocytic sorting adaptor stonin 2.

The Journal of cell biology - 31 Dec 2007

Jung Nadja, Wienisch Martin, Gu Mingyu, Rand James B, Müller Sebastian L, Krause Gerd, Jorgensen Erik M, Klingauf Jürgen, Haucke Volker

Abstract excerpt

Synaptic transmission depends on clathrin-mediated recycling of synaptic vesicles (SVs). How select SV proteins are targeted for internalization has remained elusive. Stonins are evolutionarily conserved adaptors dedicated to endocytic sorting of the SV protein synaptotagmin. Our data identify the molecular determinants for recognition of synaptotagmin by stonin 2 or its Caenorhabditis elegans orthologue UNC-41B....

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Share to Adaptor Proteins, Vesicular Transport
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18166656
DOI: 10.1083/jcb.200708107
PMCID: PMC2373488

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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