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Article

CSN complex controls the stability of selected synaptic proteins via a torsinA-dependent process.

The EMBO journal - 5 Jan 2011

Granata Alessandra, Koo Seong Joo, Haucke Volker, Schiavo Giampietro, Warner Thomas T

Abstract excerpt

DYT1 dystonia is caused by an autosomal dominant mutation that leads to a glutamic acid deletion in torsinA (TA), a member of the AAA+ ATPase superfamily. In this study, we identified a novel-binding partner of TA, the subunit 4 (CSN4) of CSN signalosome. TA binds CSN4 and the synaptic regulator...

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Identifiers

PMID: 21102408
DOI: 10.1038/emboj.2010.285
PMCID: PMC3020110

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21102408-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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