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Article

Differential expression and function of synaptotagmin 1 isoforms in Caenorhabditis elegans.

Molecular and cellular neurosciences - 1 Apr 2007

Mathews Eleanor A, Mullen Gregory P, Crowell John A, Duerr Janet S, McManus John R, Duke Angie, Gaskin Jennifer, Rand James B

Abstract excerpt

Synaptotagmin 1, encoded by the snt-1 gene in Caenorhabditis elegans, is a major synaptic vesicle protein containing two Ca(2+)-binding (C2) domains. Alternative splicing gives rise to two synaptotagmin 1 isoforms, designated SNT-1A and SNT-1B, which differ in amino acid sequence in the third, fourth, and fifth beta-strands of the second C2 domain (C2B). We report here that expression of either SNT-1 isoform...

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Identifiers

PMID: 17321753
DOI: 10.1016/j.mcn.2007.01.009
PMCID: PMC1913767

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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