Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MacroH2A1 knockdown effects on the Peg3 imprinted domain.

BMC genomics - 31 Dec 2007

Choo Jung Ha, Kim Jeong Do, Kim Joomyeong

Abstract excerpt

BACKGROUND: MacroH2A1 is a histone variant that is closely associated with the repressed regions of chromosomes. A recent study revealed that this histone variant is highly enriched in the inactive alleles of Imprinting Control Regions (ICRs). RESULTS: The current study investigates the potential roles of macroH2A1 in genomic imprinting by lowering the cellular levels of the macroH2A1 protein. RNAi-based...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromatin Immunoprecipitation
Share to DNA Methylation
Share to Down-Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genomic Imprinting

Share to Histones

Share to Kruppel-Like Transcription Factors

Share to Protein Structure, Tertiary

Share to RNA Interference

Source

Open in PubMed Open full text

Identifiers

PMID: 18166131
DOI: 10.1186/1471-2164-8-479
PMCID: PMC2241636

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MacroH2A1 knockdown effects on the Peg3 imprinted domain.PMID 18166131Read ↗

The histone variant macroH2A is an epigenetic regulator of key developmental genes.Semantic proximity Read ↗

Allele-specific deposition of macroH2A1 in imprinting control regions.Semantic proximity Read ↗

MacroH2A in stem cells: a story beyond gene repression.Semantic proximity Read ↗

Histone variant macroH2A contains two distinct macrochromatin domains capable of directing macroH2A to the inactive X chromosome.Semantic proximity Read ↗

macroH2A1 histone variants are depleted on active genes but concentrated on the inactive X chromosome.Semantic proximity Read ↗

Developmental changes in histone macroH2A1-mediated gene regulation.Semantic proximity Read ↗

Histone H2A variants and the inactive X chromosome: identification of a second macroH2A variant.Semantic proximity Read ↗

Genome-wide distribution of macroH2A1 histone variants in mouse liver chromatin.Semantic proximity Read ↗

The Histone Variant MacroH2A Blocks Cellular Reprogramming by Inhibiting Mesenchymal-to-Epithelial Transition.Semantic proximity Read ↗

The histone H2A variant macroH2A1 does not localize to the centrosome.Semantic proximity Read ↗

Integrative CUT&Tag/RNA-Seq analysis of histone variant macroH2A1-dependent orchestration of human iPSCs reprogrammingSemantic proximity Read ↗

Synergism between DNA methylation and macroH2A1 occupancy in epigenetic silencing of the tumor suppressor gene p16(CDKN2A).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.