Article
Allele-specific deposition of macroH2A1 in imprinting control regions.
Human molecular genetics - 1 Mar 2006
Choo Jung Ha, Kim Jeong Do, Chung Jae Hoon, Stubbs Lisa, Kim Joomyeong
Abstract excerpt
In the current study, we analyzed the deposition patterns of macroH2A1 at a number of different genomic loci located in X chromosome and autosomes. MacroH2A1 is preferentially deposited at methylated CpG-rich regions located close to promoters. The macroH2A1 deposition patterns at the methylated CpG islands of several imprinted domains, including the imprinting control regions (ICRs) of Xist, Peg3, H19/Igf2,...
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