Article
Shared and unique susceptibility genes in a mouse model of Graves' disease determined in BXH and CXB recombinant inbred mice.
Endocrinology - 1 Apr 2008
McLachlan Sandra M, Aliesky Holly A, Pichurin Pavel N, Chen Chun-Rong, Williams Robert W, Rapoport Basil
Abstract excerpt
Susceptibility genes for TSH receptor (TSHR) antibodies and hyperthyroidism can be probed in recombinant inbred (RI) mice immunized with adenovirus expressing the TSHR A-subunit. The RI set of CXB strains, derived from susceptible BALB/c and resistant C57BL/6 (B6) mice, were studied previously. High-resolution genetic maps are also available for RI BXH strains, derived from B6 and C3H/He parents. We found that...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
