Article
Effects of genetic immunization of Swiss outbred mice with human thyroid stimulating hormone receptor cDNA plasmids harboring gain-of-function mutations.
Journal of molecular endocrinology - 1 Feb 2007
Ho Su-Chin, Goh Sui-Sin, Kee Irene H C, Chow Pierce K H, Yeo Chin-Pin, Khoo Daphne H C
Abstract excerpt
Animal models of Graves' disease have been generated in recent years with various vaccination protocols using wild-type TSH receptor. In this study, we report the findings of genetic immunization of Swiss outbred mice with three different mutated human TSH receptor plasmids, each containing one c...
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