Article
Differential Susceptibility of BALB/c and BALB/cBy mice to Graves' hyperthyroidism.
Thyroid : official journal of the American Thyroid Association - 1 Jul 2006
Seetharamaiah Gattadahalli S, Land Kimberly J
Abstract excerpt
BALB/c mice are susceptible to the induction of Graves' hyperthyroidism. To investigate the susceptibility of BALB/c substrains of mice to the induction of hyperthyroidism, we immunized BALB/cJ and BALB/cByJ mice with an adenovirus expressing amino acid residues 1-289 of thyrotropin receptor (TSHR). The data presented in this article showed that 17 of 26 (65%) BALB/c and only 4 of 30 (13%) BALB/cBy mice developed...
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