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Article

[Variable-regions of immunoglobulin H-chain genes encoding anti-TSH receptor antibodies].

Nihon rinsho. Japanese journal of clinical medicine - 1 Apr 1994

Matsuda F

Abstract excerpt

We have established EBV-transformed human B cell clones producing monoclonal anti-TSH receptor antibodies from two patients with Graves' disease. We then isolated and characterized immunoglobulin VH genes of 5 B cell clones with the TBII activity and 4 B cell clones with the TSAb activity. We fou...

Topics

Autoantibodies
B-Lymphocytes
Genes, Immunoglobulin
Graves Disease
Humans
Immunoglobulin Heavy Chains
Immunoglobulins, Thyroid-Stimulating
Mutation
Receptors, Thyrotropin

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 7910858

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7910858-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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