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Article

Association of MAPT haplotype-tagging SNPs with sporadic Parkinson's disease.

Neurobiology of aging - 1 Sept 2009

Vandrovcova Jana, Pittman Alan M, Malzer Elke, Abou-Sleiman Patrick M, Lees Andrew J, Wood Nicholas W, de Silva Rohan

Abstract excerpt

Mutations in the tau gene (MAPT) have been found in families with frontotemporal dementia with parkinsonism linked to chromosome 17. In addition, the MAPT H1-clade specific sub-haplotype, H1c, has been strongly associated with the tauopathies, progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) and, to a lesser extent, with Alzheimer's disease (AD). In Parkinson's disease (PD), there have...

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Source

Identifiers

PMID: 18162161
DOI: 10.1016/j.neurobiolaging.2007.11.019

Genes

MAPT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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