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Article

Navigating the ALS Genetic Labyrinth: The Role of MAPT Haplotypes.

Genes - 30 Oct 2023

Tourtourikov Ivan, Dabchev Kristiyan, Todorov Tihomir, Angelov Teodor, Chamova Teodora, Tournev Ivailo, Kadiyska Tanya, Mitev Vanyo, Todorova Albena

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by wide clinical and biological heterogeneity, with a large proportion of ALS patients also exhibiting frontotemporal dementia (FTD) spectrum symptoms. This project aimed to characterize risk subtypes of the H1 haplotype within the MAPT (microtubule-associated protein tau) gene, according to their possible effect as a risk factor and...

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Identifiers

PMID: 38002967
DOI: 10.3390/genes14112023
PMCID: PMC10671552

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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