Article
Different MAPT haplotypes are associated with Parkinson's disease and progressive supranuclear palsy.
Neurobiology of aging - 1 Mar 2011
Ezquerra Mario, Pastor Pau, Gaig Carles, Vidal-Taboada Jose M, Cruchaga Carlos, Muñoz Esteban, Martí Maria-Jose, Valldeoriola Francesc, Aguilar Miquel, Calopa Matilde, Hernandez-Vara Jorge, Tolosa Eduardo
Abstract excerpt
The H1 MAPT haplotype in the 17q21 chromosomal region has been associated with several neurodegenerative diseases. Some reports have suggested that there is an association between genetic variants within the H1 haplotype with Parkinson's disease (PD), progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD). Here we report a genetic association study using seven SNPs located along the 17q21...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
