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Article

Heterozygous rare genetic variants in non-syndromic early-onset obesity

29 Mar 2019

Abstract excerpt

BACKGROUND: Obesity is a very heterogeneous disorder at both the clinical and molecular levels and with high heritability. Several monogenic forms and genes with strong effects have been identified for non-syndromic severe obesity. Novel therapeutic interventions are in development for some genetic forms, emphasizing the importance of determining genetic contributions. OBJECTIVE: We aimed to define the...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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PMID: 30926952
DOI: 10.1038/s41366-019-0357-5

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