Article
FTO: the first gene contributing to common forms of human obesity.
Obesity reviews : an official journal of the International Association for the Study of Obesity - 1 May 2008
Loos R J F, Bouchard C
Abstract excerpt
Genome-wide association, the latest gene-finding strategy, has led to the first major success in the field of obesity genetics with the discovery of FTO (fat mass and obesity associated gene) as an obesity-susceptibility gene. A cluster of variants in the first intron of FTO showed a strong and highly significant association with obesity-related traits in three independent genome-wide association studies, a...
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