Article
'Fat mass and obesity associated' gene (FTO): no significant association of variant rs9939609 with weight loss in a lifestyle intervention and lipid metabolism markers in German obese children and adolescents.
BMC medical genetics - 17 Sept 2008
Müller Timo D, Hinney Anke, Scherag André, Nguyen Thuy T, Schreiner Felix, Schäfer Helmut, Hebebrand Johannes, Roth Christian L, Reinehr Thomas
Abstract excerpt
BACKGROUND: We have previously identified strong association of six single nucleotide polymorphisms (SNPs) in FTO (fat mass and obesity associated gene) to early onset extreme obesity within the first genome wide association study (GWA) for this phenotype. The aim of this study was to investigate whether the obesity risk allele of one of these SNPs (rs9939609) is associated with weight loss in a lifestyle...
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