Article
[p53 Codon 72 and 16-bp duplication polymorphisms of gastric cancer in Koreans].
The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi - 1 Nov 2007
Kim Jung Mi, Lee Oh Young, Lee Chun Geun, Kwon Sung Joon, Kim Kyung Suk, Moon Won, Koh Dong Hee, Lee Hang Lak, Yoon Byoeng Chul, Choi Ho Soon, Hahm Joon Soo, Lee Min Ho, Lee Dong Hoo
Abstract excerpt
BACKGROUND/AIMS: p53 gene plays an important role in cell cycle control in response to DNA damage which may increase the probability of mutations leading to carcinogenesis. The role of p53 gene polymorphisms [codon 72 (exon 4) and 16-bp duplication (intron 3)] as potential markers indicating cancer risk remains inconclusive, and the data on gastric cancer are very limited. The aim of this study was to assess the...
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