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Intron 3 16 bp duplication polymorphism of TP53 contributes to cancer susceptibility: a meta-analysis.

Carcinogenesis - 1 Apr 2010

Hu Zheng, Li Xiang, Qu Xincai, He Yungang, Ring Brian Z, Song Enmin, Su Li

Abstract excerpt

A few genetic polymorphisms of TP53 are known to have a significant effect on cancer susceptibility. Intron 3 16 bp duplication polymorphism of TP53 has been reported to be associated with breast cancer, colorectal cancer, lung cancer and other cancers, but the reported results remain inconclusive. The present study, a meta-analysis including a total of 9801 cases and 10,391 controls from 26 studies, revealed...

Topics

Gene Duplication
Genes, p53
Genetic Predisposition to Disease
Humans
Introns
Neoplasms
Polymorphism, Genetic
Publication Bias

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 20089604
DOI: 10.1093/carcin/bgq018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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