Article
Intron 3 sixteen base pairs duplication polymorphism of p53 contributes to breast cancer susceptibility: evidence from meta-analysis.
PloS one - 1 Jan 2013
Wu Dongmei, Zhang Zhizhong, Chu Haiyan, Xu Ming, Xue Yao, Zhu Haixia, Zhang Zhengdong
Abstract excerpt
BACKGROUND: P53 is a tumor suppressor gene and plays important role in the etiology of breast cancer. Intron 3 sixteen-bp duplication polymorphism of p53 has been reported to be associated with breast cancer risk. However, the reported results remain conflicting rather than conclusive. METHODS: A meta-analysis including 19 case-control studies was performed to address this issue. Odds ratios (ORs) with 95%...
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