Article
Catalytic inactive heme oxygenase-1 protein regulates its own expression in oxidative stress.
Free radical biology & medicine - 1 Mar 2008
Lin Qing S, Weis Sebastian, Yang Guang, Zhuang Tiangang, Abate Aida, Dennery Phyllis A
Abstract excerpt
Heme oxygenase-1 (HO-1) catalyzes the degradation of heme and forms antioxidant bile pigments as well as the signaling molecule carbon monoxide. HO-1 is inducible in response to a variety of chemical and physical stress conditions to function as a cytoprotective molecule. Therefore, it is importa...
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