Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Heme Oxygenase -1 Gene Therapy: Recent Advances and Therapeutic Applications

1 Apr 2007

Abstract excerpt

Heme oxygenase-1 (HO-1) is regarded as a sensitive and reliable indicator of cellular oxidative stress. Studies on carbon monoxide (CO) and bilirubin, two of the three (iron is the third) end products of heme degradation have improved the understanding of the protective role of HO against oxidative injury. CO is a vasoactive molecule and bilirubin is an antioxidant, and an increase in their production through an...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Heme Oxygenase-1 and Carbon Monoxide
Share to Hemoglobin structure and function
Share to Neonatal Health and Biochemistry

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17430129
DOI: 10.2174/156652307780363134

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Heme Oxygenase -1 Gene Therapy: Recent Advances and Therapeutic ApplicationsPMID 17430129Read ↗

The role of heme oxygenase-1 in pulmonary disease.Semantic proximity Read ↗

Hypoxia-inducible plasmid expressing both miSHP-1 and HO-1 for the treatment of ischemic diseaseSemantic proximity Read ↗

Catalytic inactive heme oxygenase-1 protein regulates its own expression in oxidative stress.Semantic proximity Read ↗

Human heme oxygenase: Cell cycle‐dependent expression and DNA microarray identification of multiple gene responses after transduction of endothelial cellsSemantic proximity Read ↗

Endothelial Effects of Simultaneous Expression of Human HO-1, E5NT, and ENTPD1 in a MouseSemantic proximity Read ↗

Adenovirus-mediated expression of the HO-1 protein within MSCs decreased cytotoxicity and inhibited apoptosis induced by oxidative stressesSemantic proximity Read ↗

Divergent cardiopulmonary actions of heme oxygenase enzymatic products in chronic hypoxia.Semantic proximity Read ↗

Gene electro-transfer of an improved erythropoietin plasmid in mice and non-human primatesSemantic proximity Read ↗

Heme oxygenase-1 deficiency accelerates formation of arterial thrombosis through oxidative damage to the endothelium, which is rescued by inhaled carbon monoxide.Semantic proximity Read ↗

The preparation of rat heme oxygenase-1 mutant to reduce the level of bilirubin.Semantic proximity Read ↗

Nitric Oxide Synthase Gene Therapy for Cardiovascular DiseaseSemantic proximity Read ↗

Heme Oxygenase-1 and Its Metabolites Carbon Monoxide and Biliverdin, but Not Iron, Exert Antiviral Activity against Porcine Circovirus Type 3Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.