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Article

Genetic Diversity in Drug Transporters: Impact in African Populations

26 Feb 2020

Abstract excerpt

Polymorphisms in drug transporters, like the adenosine triposphate-binding cassette (ABC) and solute carrier (SLC) superfamilies, may contribute to the observed diversity in drug response in African patients. This review aims to provide a comprehensive summary and analysis of the frequencies and distributions in African populations of ABC and SLC variants that affect drug pharmacokinetics (PK) and...

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PMID: 32100958
DOI: 10.1111/cts.12769

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