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Article

Differential GATA factor stabilities: implications for chromatin occupancy by structurally similar transcription factors.

Biochemistry - 22 Jan 2008

Lurie Louis J, Boyer Meghan E, Grass Jeffrey A, Bresnick Emery H

Abstract excerpt

Whereas the transcription factors GATA-1 and GATA-2 function both uniquely and redundantly to control blood cell development, the process termed hematopoiesis, mechanisms underlying their unique versus common functions are poorly understood. We used two independent assays to demonstrate that GATA-1 is considerably more stable than GATA-2 in multiple cellular contexts, even though both factors are subject to...

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PMID: 18154321
DOI: 10.1021/bi701692p

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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