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Article

Role of the pioneer transcription factor GATA2 in health and disease.

Journal of molecular medicine (Berlin, Germany) - 1 Oct 2023

Aktar Amena, Heit Bryan

Abstract excerpt

The transcription factor GATA2 is involved in human diseases ranging from hematopoietic disorders, to cancer, to infectious diseases. GATA2 is one of six GATA-family transcription factors that act as pioneering transcription factors which facilitate the opening of heterochromatin and the subsequent binding of other transcription factors to induce gene expression from previously inaccessible regions of the genome....

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Source

Identifiers

PMID: 37624387
DOI: 10.1007/s00109-023-02359-8

Genes

GATA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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